Publicaciones - Red Temática de investigación cooperativa en cáncer

PUBLICACIONES

RD12/0036/0053

Adherence to capecitabine in preoperative treatment of stage II and III rectal cancer: do we need to worry?

Font R, Espinas JA, Layos L, Martinez Villacampa M, Capdevila J, Tobeña M, Pisa A, Pericay C, Lezcano C, Fort E, Cardona I, Berga N, Solà J, Borras JM

Ann Oncol 2017. 4. 831-835. PMID: 28327898.

RD12/0036/0053

Understanding variations in the use of hypofractionated radiotherapy and its specific indications for breast cancer: A mixed-methods study.

Prades J, Algara M, Espinàs JA, Farrús B, Arenas M, Reyes V, García-Reglero V, Cambra MJ, Rubio E, Anglada L, Eraso A, Pedro A, Fuentes-Raspall MJ, Tuset V, Solà J, Borras JM

Radiother Oncol 2017. 1. 22-28. PMID: 28236538.

RD12/0036/0053

Current developments in cancer care: including the patients' perspective-3rd European Roundtable Meeting (ERTM) June 17, 2016, Berlin, Germany.

Ortmann O, Rösler W, Helbig U, participants of the ERTM.

J Cancer Res Clin Oncol 2017. 4. 673-676. PMID: 27988842.

RD12/0036/0005

Snail1-expressing fibroblasts as a source of paracrine signals in colon cancer tumors

Herrera A, Herrera M, Alba-Castellón L, Silva J, García V, Loubat J, Alvarez-Cienfuegos A, García JM, Rodríguez R, Gil B, Citores MJ, Larriba MJ, Casal JI, García de Herreros A, Bonilla F, Peña C

2014.

Grupos colaboradores: RD12/0036/0005 , RD12/0036/0041

RD12/0036/0005

The Epithelial-to-Mesenchymal Transition (EMT), a Particular Case.

Cebrià-Costa JP, Millanes-Romero A, de Herreros AG, Peiró S

Mol Cell Oncol 2014. 2. e960770. PMID: 27308335.

RD12/0036/0005

Snail1 controls cooperative cell plasticity during metastasis.

Baulida J

Oncoscience 2015. 11. 898-9. PMID: 26697515.

RD12/0036/0005

Lysyl oxidase-like 2 (LOXL2) oxidizes trimethylated lysine 4 in histone H3.

Herranz N, Dave N, Millanes-Romero A, Pascual-Reguant L, Morey L, Díaz VM, Lórenz-Fonfría V, Gutierrez-Gallego R, Jerónimo C, Iturbide A, Di Croce L, García de Herreros A, Peiró S

FEBS J 2016. 23. 4263-4273. PMID: 27735137.

RD12/0036/0005

Pharmacological Approaches in an Experimental Model of Non-Small Cell Lung Cancer: Effects on Tumor Biology.

Mateu-Jimenez M, Fermoselle C, Rojo F, Mateu J, Peña R, Urtreger AJ, Diament MJ, Joffé ED, Pijuan L, Herreros AG, Barreiro E

Curr Pharm Des 2016. 34. 5300-5310. PMID: 27339432.

Grupos colaboradores: RD12/0036/0005 , RD12/0036/0051

RD12/0036/0005

Snail1-Dependent Activation of Cancer-Associated Fibroblast Controls Epithelial Tumor Cell Invasion and Metastasis.

Alba-Castellón L, Olivera-Salguero R, Mestre-Farrera A, Peña R, Herrera M, Bonilla F, Casal JI, Baulida J, Peña C, García de Herreros A

Cancer Res 2016. 21. 6205-6217. PMID: 27503928.

Grupos colaboradores: RD12/0036/0005 , RD12/0036/0041

RD12/0036/0005

Antisense non-coding RNAs and regulation of gene transcription.

Beltran M, García de Herreros A

Transcription 2016. 2. 39-43. PMID: 26985653.

RD12/0036/0005

A Switch in Akt Isoforms Is Required for Notch-Induced Snail1 Expression and Protection from Cell Death.

Frías A, Lambies G, Viñas-Castells R, Martínez-Guillamon C, Dave N, García de Herreros A, Díaz VM

Mol Cell Biol 2015. 6. 923-40. PMID: 26711268.

RD12/0036/0005

F-box proteins: Keeping the epithelial-to-mesenchymal transition (EMT) in check.

Díaz VM, de Herreros AG

Semin Cancer Biol 2016. 71-9. PMID: 26506454.

RD12/0036/0007

EMT: Present and future in clinical oncology.

Santamaria PG, Moreno-Bueno G, Portillo F, Cano A

Mol Oncol 2017. 7. 718-738. PMID: 28590039.

RD12/0036/0007

Lysyl oxidase-like protein LOXL2 promotes lung metastasis of breast cancer.

Salvador F, Martin A, López-Menéndez C, Moreno-Bueno G, Santos V, Vazquez-Naharro A, Santamaría PG, Morales S, Dubus P, Muinelo-Romay L, López López R, Tung JC, Weaver VM, Portillo F, Cano A

Cancer Res 2017. PMID: 28720577.

RD12/0036/0005

Tubular Cytoplasmic Expression of Zinc Finger Protein SNAI1 in Renal Transplant Biopsies: A Sign of Diseased Epithelial Phenotype?

Prunotto M, Chaykovska L, Bongiovanni M, Frattini M, Cagarelli T, Weibel F, Bruschi M, de Herreros AG, Moll S

Am J Pathol 2017. 1. 55-69. PMID: 27863213.

RD12/0036/0005

Activation of CK1? by PP2A/PR61? is required for the initiation of Wnt signaling.

Vinyoles M, Del Valle-Pérez B, Curto J, Padilla M, Villarroel A, Yang J, de Herreros AG, Duñach M

Oncogene 2017. 3. 429-438. PMID: 27321178.

RD12/0036/0005

Epithelial-to-mesenchymal transition transcription factors in cancer-associated fibroblasts.

Baulida J

Mol Oncol 2017. 7. 847-859. PMID: 28544627.

RD12/0036/0005

Epithelial-mesenchymal transition in cancer.

Moustakas A, de Herreros AG

Mol Oncol 2017. 7. 715-717. PMID: 28677253.

RD12/0036/0005

p120-catenin in canonical Wnt signaling.

Duñach M, Del Valle-Pérez B, García de Herreros A

Crit Rev Biochem Mol Biol 2017. 3. 327-339. PMID: 28276699.

RD12/0036/0052

Donor CTLA-4 Genotype Modulates the Immune Response to Minor Histocompatibility Antigen Mismatches.

Gallardo D, Bosch-Vizcaya A, Rodríguez-Romanos R, Santos N, Buño I, de la Cámara R, Brunet S, Jiménez-Velasco A, González M, Nieto JB, Martínez-Laperche C, Vallejo C, Ferrá C, Sampol A, López-Jiménez J, Pérez-Simón JA, Martínez C, Díez JL, GvHD/Immunotherapy Committee of the Spanish Hematopoietic Transplant Group.

Biol Blood Marrow Transplant 2017. PMID: 28827064.

Grupos colaboradores: RD12/0036/0069 , RD12/0036/0052

RD12/0036/0014

A retrospective study of pregnancy-associated atypical hemolytic uremic syndrome.

Huerta A, Arjona E, Portoles J, Lopez-Sanchez P, Rabasco C, Espinosa M, Cavero T, Blasco M, Cao M, Manrique J, Cabello-Chavez V, Suñer M, Heras M, Fulladosa X, Belmar L, Sempere A, Peralta C, Castillo L, Arnau A, Praga M, Rodriguez de Cordoba S

Kidney Int 2017. PMID: 28911789.

RD12/0036/0014

Single- or double-unit UCBT following RIC in adults with AL: a report from Eurocord, the ALWP and the CTIWP of the EBMT.

Baron F, Ruggeri A, Beohou E, Labopin M, Mohty M, Blaise D, Cornelissen JJ, Chevallier P, Sanz G, Petersen E, Savani BN, Gluckman E, Nagler A

J Hematol Oncol 2017. 1. 128. PMID: 28637512.

RD12/0036/0014

Blinatumomab versus Chemotherapy for Advanced Acute Lymphoblastic Leukemia.

Kantarjian H, Stein A, Gökbuget N, Fielding AK, Schuh AC, Ribera JM, Wei A, Dombret H, Foà R, Bassan R, Arslan Ö, Sanz MA, Bergeron J, Demirkan F, Lech-Maranda E, Rambaldi A, Thomas X, Horst HA, Brüggemann M, Klapper W, Wood BL, Fleishman A, Nagorsen D, Holland C, Zimmerman Z, Topp MS

N Engl J Med 2017. 9. 836-847. PMID: 28249141.

RD12/0036/0014

Midostaurin plus Chemotherapy for Acute Myeloid Leukemia with a FLT3 Mutation.

Stone RM, Mandrekar SJ, Sanford BL, Laumann K, Geyer S, Bloomfield CD, Thiede C, Prior TW, Döhner K, Marcucci G, Lo-Coco F, Klisovic RB, Wei A, Sierra J, Sanz MA, Brandwein JM, de Witte T, Niederwieser D, Appelbaum FR, Medeiros BC, Tallman MS, Krauter J, Schlenk RF, Ganser A, Serve H, Ehninger G, Amadori S, Larson RA, Döhner H

N Engl J Med 2017. 5. 454-464. PMID: 28644114.

RD12/0036/0014

Infectious Complications after Umbilical Cord-Blood Transplantation from Unrelated Donors.

Montoro J, Piñana JL, Moscardó F, Sanz J

Mediterr J Hematol Infect Dis 2016. 1. e2016051. PMID: 27872731.

RD12/0036/0014

Haplo-Cord transplantation compared to haploidentical transplantation with post-transplant cyclophosphamide in patients with AML.

Kwon M, Bautista G, Balsalobre P, Sánchez-Ortega I, Montesinos P, Bermúdez A, de Laiglesia A, Herrera P, Martin C, Humala K, Zabalza A, Torres M, Bento L, Corral LL, Heras I, Serrano D, Buño I, Anguita J, Regidor C, Duarte R, Cabrera R, Gayoso J, Diez-Martin JL

Bone Marrow Transplant 2017. 8. 1138-1143. PMID: 28346415.

RD12/0036/0014

Characterization of three new HLA Class I Alleles in Spanish Caucasians, HLA-A*02:620, HLA-B*27:150 and HLA-B*07:05:01:02.

Balas A, Planelles D, Montesinos P, Solano C, Vicario JL

Int J Immunogenet 2017. 3. 148-150. PMID: 28383785.

RD12/0036/0014

Long-term outcome of older patients with newly diagnosed de novo acute promyelocytic leukemia treated with ATRA plus anthracycline-based therapy.

Martínez-Cuadrón D, Montesinos P, Vellenga E, Bernal T, Salamero O, Holowiecka A, Brunet S, Gil C, Benavente C, Ribera JM, Pérez-Encinas M, De la Serna J, Esteve J, Rubio V, González-Campos J, Escoda L, Amutio ME, Arnan M, Arias J, Negri S, Lowënberg B, Sanz MA

Leukemia 2017. PMID: 28584252.

RD12/0036/0014

Predictors of thrombohemorrhagic early death in children and adolescents with t(15;17)-positive acute promyelocytic leukemia treated with ATRA and chemotherapy.

Abla O, Ribeiro RC, Testi AM, Montesinos P, Creutzig U, Sung L, Di Giuseppe G, Stephens D, Feusner JH, Powell BL, Hasle H, Kaspers GJL, Dalla-Pozza L, Lassaletta A, Tallman MS, Locatelli F, Reinhardt D, Lo-Coco F, Hitzler J, Sanz MA

Ann Hematol 2017. 9. 1449-1456. PMID: 28597167.

RD12/0036/0014

Real life experience with frontline azacitidine in a large series of older adults with acute myeloid leukemia stratified by MRC/LRF score: results from the expanded international E-ALMA series (E-ALMA+).

Falantes J, Pleyer L, Thépot S, Almeida AM, Maurillo L, Martínez-Robles V, Stauder R, Itzykson R, Pinto R, Venditti A, Bargay J, Burgstaller S, Martínez MP, Seegers V, Cortesão E, Foncillas MÁ, Gardin C, Montesinos P, Musto P, Fenaux P, Greil R, Sanz MA, Ramos F, European ALMA?+?Investigators.

Leuk Lymphoma 2017. 1-8. PMID: 28838276.

RD12/0036/0014

Impact of novel polymorphisms related to cytotoxicity of cytarabine in the induction treatment of acute myeloid leukemia.

Megías-Vericat JE, Montesinos P, Herrero MJ, Moscardó F, Bosó V, Martínez-Cuadrón D, Poveda JL, Sanz MÁ, Aliño SF

Pharmacogenet Genomics 2017. 7. 270-274. PMID: 28570300.

RD12/0036/0014

Validation of R-MIPI and prognostic value of immunoglobulin light chain restriction in mantle cell lymphoma.

Villegas Da Ros C, Linares Garcia M, Ortiz Zuluaga S, Javier Gonzalez K, Costa S, Roig M, Perez Rodriguez PL, Orero Castello M, Luna I, López-Pavía M, Sanchez M, Carbonell F

Br J Haematol 2017. 5. 816-818. PMID: 27125335.

RD12/0036/0014

Impact of azacitidine on red blood cell alloimmunisation in myelodysplastic syndrome.

Ortiz S, Orero MT, Javier K, Villegas C, Luna I, Pérez P, Roig M, López M, Costa S, Carbonell F, Collado R, Ivars D, Linares M

Blood Transfus 2017. 5. 472-477. PMID: 27416573.

RD12/0036/0014

Autologous Stem Cell Transplantation for Follicular Lymphoma: Favorable Long-Term Survival Irrespective of Pretransplantation Rituximab Exposure.

Jiménez-Ubieto A, Grande C, Caballero D, Yáñez L, Novelli S, Hernández-Garcia MT, Manzanares M, Arranz R, Ferreiro JJ, Bobillo S, Mercadal S, Galeo A, López Jiménez J, Moraleda JM, Vallejo C, Albo C, Pérez E, Marrero C, Magnano L, Palomera L, Jarque I, Martínez-Sánchez P, Martín A, Coria E, López-Guillermo A, Salar A, Lahuerta JJ

Biol Blood Marrow Transplant 2017. 10. 1631-1640. PMID: 28533060.

RD12/0036/0014

IgG subclasses quantitation: Analytical performance of The Binding Site SPA_PLUS® human assay and comparison with Siemens BNII® assay.

Sarnago A, Pascual RM, Moreno MJ, Laíz B, Fuster O

Clin Biochem 2017. PMID: 28912097.

RD12/0036/0014

Circulating MicroRNAs as Novel Biomarkers of Stenosis Progression in Asymptomatic Carotid Stenosis.

Dolz S, Górriz D, Tembl JI, Sánchez D, Fortea G, Parkhutik V, Lago A

Stroke 2017. 1. 10-16. PMID: 27899750.

RD12/0036/0014

Randomized phase 2 study: elotuzumab plus bortezomib/dexamethasone vs bortezomib/dexamethasone for relapsed/refractory MM.

Jakubowiak A, Offidani M, Pégourie B, De La Rubia J, Garderet L, Laribi K, Bosi A, Marasca R, Laubach J, Mohrbacher A, Carella AM, Singhal AK, Tsao LC, Lynch M, Bleickardt E, Jou YM, Robbins M, Palumbo A

Blood 2016. 23. 2833-40. PMID: 27091875.

RD12/0036/0014

Secondary thrombotic microangiopathy and eculizumab: A reasonable therapeutic option.

Román E, Mendizábal S, Jarque I, de la Rubia J, Sempere A, Morales E, Praga M, Ávila A, Górriz JL

Nefrologia 2017. 5. 478-491. PMID: 28946961.

RD12/0036/0014

Influence of cytarabine metabolic pathway polymorphisms in acute myeloid leukemia induction treatment.

Megías-Vericat JE, Montesinos P, Herrero MJ, Moscardó F, Bosó V, Martínez-Cuadrón D, Rojas L, Rodríguez-Veiga R, Boluda B, Sendra L, Cervera J, Poveda JL, Sanz MÁ, Aliño SF

Leuk Lymphoma 2017. 12. 2880-2894. PMID: 28573946.

RD12/0036/0014

Mutations in TP53 and JAK2 are independent prognostic biomarkers in B-cell precursor acute lymphoblastic leukaemia.

Forero-Castro M, Robledo C, Benito R, Bodega-Mayor I, Rapado I, Hernández-Sánchez M, Abáigar M, Maria Hernández-Sánchez J, Quijada-Álamo M, María Sánchez-Pina J, Sala-Valdés M, Araujo-Silva F, Kohlmann A, Luis Fuster J, Arefi M, de Las Heras N, Riesco S, Rodríguez JN, Hermosín L, Ribera J, Camos Guijosa M, Ramírez M, de Heredia Rubio CD, Barragán E, Martínez J, Ribera JM, Fernández-Ruiz E, Hernández-Rivas JM

Br J Cancer 2017. 2. 256-265. PMID: 28557976.

RD12/0036/0014

Comparative genomic analysis of PML and RARA breakpoints in paired diagnosis/relapse samples of patients with acute promyelocytic leukemia treated with all-trans retinoic acid and chemotherapy.

Iaccarino L, Ottone T, Hasan SK, Divona M, Cicconi L, Lavorgna S, Alfonso V, Basso G, Barragán E, Bocchia M, Rego EM, Grimwade D, Voso MT, Lo-Coco F

Leuk Lymphoma 2017. 1-3. PMID: 28838264.

RD12/0036/0034

Klf4 and Klf5 differentially inhibit mesoderm and endoderm differentiation in embryonic stem cells.

Aksoy I, Giudice V, Delahaye E, Wianny F, Aubry M, Mure M, Chen J, Jauch R, Bogu GK, Nolden T, Himmelbauer H, Xavier Doss M, Sachinidis A, Schulz H, Hummel O, Martinelli P, Hübner N, Stanton LW, Real FX, Bourillot PY, Savatier P

Nat Commun 2014. 3719. PMID: 24770696.

RD12/0036/0034

Phacomatosis pigmentokeratotica is caused by a postzygotic HRAS mutation in a multipotent progenitor cell.

Groesser L, Herschberger E, Sagrera A, Shwayder T, Flux K, Ehmann L, Wollenberg A, Torrelo A, Bagazgoitia L, Diaz-Ley B, Tinschert S, Oschlies I, Singer S, Mickler M, Toll A, Landthaler M, Real FX, Hafner C

J Invest Dermatol 2013. 8. 1998-2003. PMID: 23337891.

RD12/0036/0034

ICAT is a novel Ptf1a interactor that regulates pancreatic acinar differentiation and displays altered expression in tumours.

Campos ML, Sánchez-Arévalo Lobo VJ, Rodolosse A, Gottardi CJ, Mafficini A, Beghelli S, Scardoni M, Bassi C, Scarpa A, Real FX

Biochem J 2013. 3. 395-405. PMID: 23339455.

RD12/0036/0034

Gata6 is required for complete acinar differentiation and maintenance of the exocrine pancreas in adult mice.

Martinelli P, Cañamero M, del Pozo N, Madriles F, Zapata A, Real FX

Gut 2013. 10. 1481-8. PMID: 23002247.

RD12/0036/0013

Proposal for the creation of a national strategy for precision medicine in cancer: a position statement of SEOM, SEAP, and SEFH.

Garrido P, Aldaz A, Vera R, Calleja MA, de Álava E, Martín M, Matías-Guiu X, Palacios J

Clin Transl Oncol 2017. PMID: 28861725.

Grupos colaboradores: RD12/0036/0017 , RD12/0036/0013

RD12/0036/0013

Metabolomic and Lipidomic Profiling Identifies The Role of the RNA Editing Pathway in Endometrial Carcinogenesis.

Altadill T, Dowdy TM, Gill K, Reques A, Menon SS, Moiola CP, Lopez-Gil C, Coll E, Matias-Guiu X, Cabrera S, Garcia A, Reventos J, Byers SW, Gil-Moreno A, Cheema AK, Colas E

Sci Rep 2017. 1. 8803. PMID: 28821813.

RD12/0036/0013

Targeted proteomics identifies proteomic signatures in liquid-biopsies of the endometrium to diagnose endometrial cancer and assist in the prediction of the optimal surgical treatment.

Martinez E, Lesur A, Devis L, Cabrera S, Matias-Guiu X, Hirschfeld M, Asberger J, van Oostrum J, Casares de Cal MLÁ, Gómez-Tato A, Reventos J, Domon B, Colas E, Gil-Moreno A

Clin Cancer Res 2017. PMID: 28790116.

RD12/0036/0013

TGF? Controls Ovarian Cancer Cell Proliferation.

Alsina-Sanchís E, Figueras A, Lahiguera A, Gil-Martín M, Pardo B, Piulats JM, Martí L, Ponce J, Matias-Guiu X, Vidal A, Villanueva A, Viñals F

Int J Mol Sci 2017. 8. PMID: 28758950.

RD12/0036/0013

Tumor Heterogeneity in Endometrial Carcinoma: Practical Consequences.

Gatius S, Cuevas D, Fernández C, Roman-Canal B, Adamoli V, Piulats JM, Eritja N, Martin-Satue M, Moreno-Bueno G, Matias-Guiu X

Pathobiology 2017. PMID: 28614814.

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