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RTICC 2013
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RESEARCH ACTIVITY OF LUNG AND UPPER RESPIRATORY TRACT TUMORS PROGRAM

Work Plan. The scientific main goals of our proposal are to understand the biological intricacies of the disease in order to develop diagnostic, prognostic or predictive markers and more successful therapies. W e are also determined to optimize preventive strategies in lung cancer. To achieve these goals we have developed a work plan which includes 6 work packages (WPs).

WP1: Molecular mechanisms of respiratory tract carcinogenesis and metastasis

WP2: Molecular and genetic profiling of early stage and biomarkers

WP3: Discovery and preclinical validation of drug targets in LC.

WP4: New therapeutic strategies

WP5: Molecular and genetic profiling of metastatic disease for predicting response and resistance to conventional and novel treatments

WP6: Lung cancer prevention. Screening of lung cancer

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RD12/0036/0038
SEOM clinical guidelines for the treatment of advanced colorectal cancer 2013.
Casado-Saenz E, Feliu J, Gomez-España MA, Sanchez-Gastaldo A, Garcia-Carbonero R
Clin Transl Oncol  2013.  12.  996-1003.  PMID: 23896865. 

RD12/0036/0038
Outcome of patients with aggressive pseudomyxoma peritonei treated by cytoreductive surgery and intraperitoneal chemotherapy.
Arjona-Sanchez A, Muñoz-Casares FC, Casado-Adam A, Sánchez-Hidalgo JM, Ayllon Teran MD, Orti-Rodriguez R, Padial-Aguado AC, Medina-Fernández J, Ortega-Salas R, Pulido-Cortijo G, Gómez-España A, Rufián-Peña S
World J Surg  2013.  6.  1263-70.  PMID: 23532601. 

RD12/0036/0038
Correlation between the complex PSA/total PSA ratio and the free PSA/total PSA ratio, sensitivity and specificity of both markers for the diagnosis of prostate cancer.
Pérez-Lanzac-Lorca A, Barco-Sánchez A, Romero E, Martinez-Peinado A, López-Elorza F, Sanchez-Sanchez E, Alvarez-Ossorio-Fernandez JL, Castiñeiras-Fernández J
Actas Urol Esp  2013.  8.  498-503.  PMID: 23639236. 

RD12/0036/0038
New insights into the role of the immune microenvironment in breast carcinoma.
de la Cruz-Merino L, Barco-Sánchez A, Henao Carrasco F, Nogales Fernández E, Vallejo Benítez A, Brugal Molina J, Martínez Peinado A, Grueso López A, Ruiz Borrego M, Codes Manuel de Villena M, Sánchez-Margalet V, Nieto-García A, Alba Conejo E, Casares Lagar N, Ibáñez Martínez J
Clin Dev Immunol  2013.  785317.  PMID: 23861693. 

RD12/0036/0038
Proteomic approaches to evaluate protein S-nitrosylation in disease.
López-Sánchez LM, López-Pedrera C, Rodríguez-Ariza A
Mass Spectrom Rev  2014.  1.  7-20.  PMID: 23775552. 

RD12/0036/0038
Panitumumab and irinotecan every 3 weeks is an active and convenient regimen for second-line treatment of patients with wild-type K-RAS metastatic colorectal cancer.
Carrato A, Gómez A, Escudero P, Chaves M, Rivera F, Marcuello E, González E, Grávalos C, Constenla M, Manzano JL, Losa F, Maurel J, Dueñas R, Massuti B, Gallego J, Aparicio J, Antón A, Aranda E
Clin Transl Oncol  2013.  9.  705-11.  PMID: 23359181. 

RD12/0036/0038
Bevacizumab plus preoperative chemotherapy in operable HER2 negative breast cancer: biomarkers and pathologic response.
Sánchez-Rovira P, Seguí MA, Llombart A, Aranda E, Antón A, Sánchez A, Lomas M, Jaén A, Fernández M, Porras I, Dalmau E, Morales S, de la Haba-Rodríguez J
Clin Transl Oncol  2013.  10.  810-7.  PMID: 23397155. 

RD12/0036/0038
Cytoreductive surgery and intraperitoneal chemotherapy for treatment of peritoneal carcinomatosis from colorectal origin.
Losa F, Barrios P, Salazar R, Torres-Melero J, Benavides M, Massuti T, Ramos I, Aranda E
Clin Transl Oncol  2014.  2.  128-40.  PMID: 23740133. 

RD12/0036/0021
Vitamin D Is a Multilevel Repressor of Wnt/b-Catenin Signaling in Cancer Cells.
Larriba MJ, González-Sancho JM, Barbáchano A, Niell N, Ferrer-Mayorga G, Muñoz A
Cancers (Basel)  2013.  4.  1242-60.  PMID: 24202444. 

RD12/0036/0013
Epithelial-to-mesenchymal transition and stem cells in endometrial cancer.
Mirantes C, Espinosa I, Ferrer I, Dolcet X, Prat J, Matias-Guiu X.
  2013.  PMID: 23845467. 

ISCII
ISCII
 
Ministerio de Economia y Competitividad
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Red Temática Investigación Cooperativa Sanitaria
Rticc 2012
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ISCII
Red Temática Investigación Cooperativa en Cáncer (RTICC)
Centro de Investigación Cáncer - Campus Miguel de Unamuno - 37007 - Salamanca
(+34) 923294803 - sec.rticc[arroba]usal.es
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