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RESEARCH ACTIVITY OF LUNG AND UPPER RESPIRATORY TRACT TUMORS PROGRAM

Work Plan. The scientific main goals of our proposal are to understand the biological intricacies of the disease in order to develop diagnostic, prognostic or predictive markers and more successful therapies. W e are also determined to optimize preventive strategies in lung cancer. To achieve these goals we have developed a work plan which includes 6 work packages (WPs).

WP1: Molecular mechanisms of respiratory tract carcinogenesis and metastasis

WP2: Molecular and genetic profiling of early stage and biomarkers

WP3: Discovery and preclinical validation of drug targets in LC.

WP4: New therapeutic strategies

WP5: Molecular and genetic profiling of metastatic disease for predicting response and resistance to conventional and novel treatments

WP6: Lung cancer prevention. Screening of lung cancer

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Introducción
Coordinador
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Intranet
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RD12/0036/0056
Correction: HPV Testing by cobas HPV Test in a Population from Catalonia.
Lloveras B, Gomez S, Alameda F, Bellosillo B, Mojal S, Muset M, Parra M, Palomares JC, Serrano S
PLoS One  2013.  10.  PMID: 24204493. 

RD12/0036/0018
Polymorphisms in genes related to one-carbon metabolism are not related to pancreatic cancer in PanScan and PanC4.
Leenders M, Bhattacharjee S, Vineis P, Stevens V, Bueno-de-Mesquita HB, Shu XO, Amundadottir L, Gross M, Tobias GS, Wactawski-Wende J, Arslan AA, Duell EJ, Fuchs CS, Gallinger S, Hartge P, Hoover RN, Holly EA, Jacobs EJ, Klein AP, Kooperberg C, LaCroix A, Li D, Mandelson MT, Olson SH, Petersen G, Risch HA, Yu K, Wolpin BM, Zheng W, Agalliu I, Albanes D, Boutron-Ruault MC, Bracci PM, Buring JE, Canzian F, Chang K, Chanock SJ, Cotterchio M, Gaziano JM, Giovanucci EL, Goggins M, Hallmans G, Hankinson SE, Hoffman-Bolton JA, Hunter DJ, Hutchinson A, Jacobs KB, Jenab M, Khaw KT, Kraft P, Krogh V, Kurtz RC, McWilliams RR, Mendelsohn JB, Patel AV, Rabe KG, Riboli E, Tjønneland A, Trichopoulos D, Virtamo J, Visvanathan K, Elena JW, Yu H, Zeleniuch-Jacquotte A, Stolzenberg-Solomon RZ
Cancer Causes Control  2013.  3.  595-602.  PMID: 23334854. 

RD12/0036/0056
Human papillomavirus detection and p16(INK4a) expression in cervical lesions: a comparative study.
Genovés J, Alameda F, Mancebo G, Solé JM, Bellosillo B, Lloveras B, Agramunt S, Baró MT, Muset M, Casado B, Serrano L, Miralpeix E, Carreras R
Hum Pathol  2014.  4.  826-33.  PMID: 24656093. 

RD12/0036/0056
Consolidation treatment with Yttrium-90 ibritumomab tiuxetan after new induction regimen in patients with intermediate- and high-risk follicular lymphoma according to the follicular lymphoma international prognostic index: a multicenter, prospective phase II trial of the Spanish Lymphoma Oncology Group.
Provencio M, Cruz Mora MÁ, Gómez-Codina J, Quero Blanco C, Llanos M, García-Arroyo FR, de la Cruz L, Gumá Padró J, Delgado Pérez JR, Sánchez A, Alvarez Cabellos R, Rueda A, Gotel (Spanish Lymphoma Oncology Group)
Leuk Lymphoma  2014.  1.  51-5.  PMID: 23573825. 

RD12/0036/0018
Intake of coffee, decaffeinated coffee, or tea does not affect risk for pancreatic cancer: results from the European Prospective Investigation into Nutrition and Cancer Study
51. Bhoo-Pathy N, Uiterwaal CS, Dik VK, Jeurnink SM, Bech BH, Overvad K, Halkjær J, Tjønneland A, Boutron-Ruault MC, Fagherazzi G, Racine A, Katzke VA, Li K, Boeing H, Floegel A, Androulidaki A, Bamia C, Trichopoulou A, Masala G, Panico S, Crosignani P, Tumino R, Vineis P, Peeters PH, Gavrilyuk O, Skeie G, Weiderpass E, Duell EJ, Arguelles M, Molina-Montes E, Navarro C, Ardanaz E, Dorronsoro M, Lindkvist B, Wallström P, Sund M, Ye W, Khaw KT, Wareham N, Key TJ, Travis RC, Duarte-Salles T, Freisling H, Licaj I, Gallo V, Michaud DS, Riboli E, Bueno-De-Mesquita HB.
Clin Gastroenterol Hepatol  2013.  11.  1486-92.  PMID: 23756220 . 

RD12/0036/0018
Photosensitizing agents and the risk of non-melanoma skin cancer: a population-based case-control study.
Robinson SN, Zens MS, Perry AE, Spencer SK, Duell EJ, Karagas MR
J Invest Dermatol  2013.  8.  1950-5.  PMID: 23344461. 

RD12/0036/0056
Survival of European patients diagnosed with myeloid malignancies: a HAEMACARE study.
Maynadié M, De Angelis R, Marcos-Gragera R, Visser O, Allemani C, Tereanu C, Capocaccia R, Giacomin A, Lutz JM, Martos C, Sankila R, Johannesen TB, Simonetti A, Sant M, HAEMACARE Working Group
Haematologica  2013.  2.  230-8.  PMID: 22983589. 

RD12/0036/0056
Survival and cure trends for European children, adolescents and young adults diagnosed with acute lymphoblastic leukemia from 1982 to 2002.
Gatta G, Rossi S, Foschi R, Trama A, Marcos-Gragera R, Pastore G, Peris-Bonet R, Stiller C, Capocaccia R, EUROCARE Working Group
Haematologica  2013.  5.  744-52.  PMID: 23403323. 

RD12/0036/0056
Rare neuroendocrine tumours: Results of the surveillance of rare cancers in Europe project.
van der Zwan JM, Trama A, Otter R, Larrañaga N, Tavilla A, Marcos-Gragera R, Dei Tos AP, Baudin E, Poston G, Links T, RARECARE WG
Eur J Cancer  2013.  11.  2565-78.  PMID: 23541566. 

RD12/0036/0056
Cancer prevalence estimates in Europe at the beginning of 2000.
Gatta G, Mallone S, van der Zwan JM, Trama A, Siesling S, Capocaccia R, EUROCARE Working Group
Ann Oncol  2013.  6.  1660-6.  PMID: 23553062. 

ISCII
ISCII
 
Ministerio de Economia y Competitividad
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Red Temática Investigación Cooperativa Sanitaria
Rticc 2012
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ISCII
Red Temática Investigación Cooperativa en Cáncer (RTICC)
Centro de Investigación Cáncer - Campus Miguel de Unamuno - 37007 - Salamanca
(+34) 923294803 - sec.rticc[arroba]usal.es
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